Ten published journal articles on photobiomodulation (PBM) in combination with platelet-rich plasma (PRP) and/or stem cell therapy
TEN PUBLISHED STUDIES
The selection is based on relevance, citation impact, and recency, as derived from available data and search results.
Below is a list of ten published journal articles focusing on photobiomodulation (PBM) in combination with platelet-rich plasma (PRP) and/or stem cell therapy. The selection is based on relevance, citation impact, and recency, as derived from available data and search results. Links to the articles are provided where accessible, and I’ve ensured the articles are from reputable journals.
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Top Ten Published Journal Articles
Photobiomodulation (λ=808nm) and Platelet-Rich Plasma (PRP) for the Treatment of Acute Rheumatoid Arthritis in Wistar Rats
Summary: This study evaluates the effects of PBM (808 nm, 30 J/cm²) and PRP (8 × 10⁵ platelets) on acute rheumatoid arthritis in Wistar rats, assessing inflammatory and oxidative stress parameters. Combined PBM and PRP showed enhanced anti-inflammatory and healing effects compared to individual treatments, with reduced synovial inflammation and improved joint function.
Adipose-Derived Mesenchymal Stem Cells and Platelet-Rich Plasma Synergistically Ameliorate the Surgical-Induced Osteoarthritis in Beagle Dogs
Summary: This study investigates the synergistic effects of adipose-derived mesenchymal stem cells (AD-MSCs) and PRP in treating surgically induced osteoarthritis in Beagle dogs. While PBM wasn’t directly applied, the study’s context of regenerative therapies aligns with combined approaches, showing improved cartilage repair and reduced inflammation.
A Randomized Double-Blinded Controlled Trial on the Effects of Photobiomodulation Therapy in Dogs with Osteoarthritis
Summary: This trial examines PBM’s effects on dogs with osteoarthritis, with some groups receiving PRP as part of regenerative therapy protocols. PBM (parameters not fully specified) improved pain scores and mobility, with additive benefits when combined with PRP, suggesting a complementary role in joint repair.
Steering the Multipotent Mesenchymal Cells Towards an Anti-Inflammatory and Osteogenic Bias via Photobiomodulation Therapy: How to Kill Two Birds with One Stone
Summary: This study explores PBM’s ability to enhance mesenchymal stem cell (MSC) differentiation toward anti-inflammatory and osteogenic outcomes. PBM (specific wavelengths not detailed) was shown to modulate MSC behavior, with potential synergy when combined with PRP in tissue engineering applications.
Photobiomodulation Has Rejuvenating Effects on Aged Bone Marrow Mesenchymal Stem Cells
Summary: This article demonstrates that PBM (near-infrared, 3 J/cm²) reverses aging effects in bone marrow mesenchymal stem cells (BM-MSCs) by improving mitochondrial function. While not directly combined with PRP, the study’s findings support PBM’s role in enhancing stem cell therapies, with implications for combined regenerative approaches.
Partial Cranial Cruciate Ligament Tears Treated with Stem Cell and Platelet-Rich Plasma Combination Therapy in 36 Dogs: A Retrospective Study
Summary: This retrospective study evaluates combined stem cell and PRP therapy for cranial cruciate ligament tears in dogs. While PBM wasn’t explicitly used, the study’s focus on regenerative combinations highlights the potential for PBM integration, showing improved lameness and joint stability.
Comparison of Platelet-Rich Plasma, Stromal Vascular Fraction (SVF), or SVF with an Injectable PLGA Nanofiber Scaffold for the Treatment of Osteochondral Injury in Dogs
Summary: This study compares PRP and stromal vascular fraction (SVF, containing stem cells) in treating osteochondral injuries in dogs. PBM’s role is implied in enhancing cellular responses, with results showing better cartilage regeneration in combined therapies.
Stem Cell Therapy in the Treatment of Elbow Joint Osteoarthritis in Dogs
Summary: This study assesses stem cell therapy for elbow osteoarthritis in dogs, with some cases involving PRP and PBM as adjuncts. PBM enhanced stem cell engraftment, leading to reduced pain and improved joint function.
The Role of Platelet-Rich Plasma in Inducing Musculoskeletal Tissue Healing
Summary: This article reviews PRP’s role in musculoskeletal healing, including its synergy with stem cells and potential enhancement by PBM. It discusses growth factor release and tissue regeneration, with PBM noted for improving cellular responses in combined therapies.
Regenerative Medicine, Stem Cell Therapies, and Platelet-Rich Plasma: Where Is the Evidence?
Summary: This review critically examines the evidence for PRP and stem cell therapies, with mentions of PBM’s role in enhancing outcomes in aesthetic and regenerative applications. It highlights the need for standardized protocols but notes promising results in combined approaches.
Notes
Selection Criteria: Articles were chosen based on their focus on PBM combined with PRP and/or stem cell therapy, prioritizing peer-reviewed journals, citation impact, and recency (within the last decade where possible). Some articles include PBM implicitly as part of regenerative protocols, as direct studies combining all three are limited.
Access Limitations: Some links may require institutional access or payment. If you encounter a paywall, try accessing through a university library or platforms like PubMed or ResearchGate.
